exRNAdisease

General Information

Database ID:

exR0410488

RNA Name:

MIRLET7BHG

RNA Type:

lncRNA

Chromosome:

chr22

Starnd:

Coordinate:

Start Site(bp):

46053869

End Site(bp):

46113928

External Links:

Disease Information

Disease Name:	Clear Cell Renal Cell Carcinoma
Disease Category:	Cancers
MeSH ID:	D002292
Type:	Neoplasms/Urogenital Neoplasms
Alias:	Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID:	GSE125442
Description:	Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma
Experimental Design:	Cancer vs Control
Case Disease Type:	Clear Cell Renal Cell Carcinoma
Case Disease SubType:	NA
Case Sample:	Clear Cell Renal Cell Carcinoma
Control Sample:	Healthy
Number of Case:	10
Number of Control:	10
Number of Samples:	20

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AGRN	chr1	1020120	1056118	+
ADAT3	chr19	1905399	1913447	+

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-98-5p	chrX	53556299	53556320	-
hsa-miR-520a-5p	chr19	53690895	53690915	+
hsa-miR-508-3p	chrX	147236945	147236967	-
hsa-let-7b-5p	chr22	46113691	46113712	+
hsa-miR-766-5p	chrX	119646799	119646820	-
hsa-miR-1306-5p	chr22	20086072	20086093	+
hsa-miR-4500	chr13	87618671	87618687	-
hsa-let-7a-5p	chr9	94175962	94175983	+
hsa-miR-29c-3p	chr1	207801865	207801886	-
hsa-miR-2116-3p	chr15	59171192	59171212	-
hsa-miR-6783-3p	chr17	44934618	44934639	-
hsa-miR-3126-5p	chr2	69103691	69103712	+
hsa-miR-3180	chr16	15154949	15154967	-
hsa-miR-874-3p	chr5	137647582	137647603	-
hsa-miR-34b-5p	chr11	111512950	111512972	+
hsa-miR-29b-3p	chr7	130877467	130877489	-
hsa-let-7f-5p	chrX	53557246	53557267	-
hsa-let-7d-5p	chr9	94178841	94178862	+
hsa-miR-183-5p	chr7	129774967	129774988	-
hsa-miR-1343-3p	chr11	34941888	34941909	+
hsa-miR-345-3p	chr14	100307912	100307933	+
hsa-let-7g-5p	chr3	52268336	52268357	-
hsa-miR-449c-5p	chr5	55172313	55172337	-
hsa-miR-330-5p	chr19	45639049	45639070	-
hsa-miR-2682-5p	chr1	98045307	98045329	-
hsa-miR-3064-5p	chr17	64500817	64500837	-
hsa-miR-2114-5p	chrX	150228016	150228037	+
hsa-miR-29a-3p	chr7	130876748	130876769	-
hsa-miR-605-3p	chr10	51299623	51299644	+
hsa-miR-132-5p	chr17	2049965	2049986	-

circRNA targets:

lncRNA targets:

Display:

Experiment Detail

GEO ID:	GSE125442
Sample Source:	Urine
Source Fraction:	Exosome
Platform:	GPL21290
Method:	NGS
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	882
Sample treatment protocol:	Exosomes were isolated by ultracentrifugation from 50-ml urine samples.
RNA Extract protocol:	A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol.
RNA library preparation protocol:	Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference