exRNAdisease

Entry Detail

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General Information

Database ID: exR0410526 RNA Name: OIP5-AS1 RNA Type: lncRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 41283990 End Site(bp): 41309737 External Links: ENSG00000247556

Disease Information

Disease Name: Clear Cell Renal Cell Carcinoma Disease Category: Cancers MeSH ID: D002292 Type: Neoplasms/Urogenital Neoplasms Alias: Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID: GSE125442 Description: Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma Experimental Design: Cancer vs Control Case Disease Type: Clear Cell Renal Cell Carcinoma Case Disease SubType: NA Case Sample: Clear Cell Renal Cell Carcinoma Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTB chr7 5527148 5563784 - AGPAT1 chr6 32168212 32178096 - AC139530.2 chr17 81703371 81720539 + ACO1 chr9 32384603 32454769 + ACTR2 chr2 65227753 65271253 + AK3 chr9 4709556 4742043 - AL136295.5 chr14 24147548 24166452 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-641 chr19 40282603 40282626 - hsa-miR-320a-3p chr8 22244975 22244996 - hsa-miR-141-3p chr12 6964155 6964176 + hsa-miR-378a-3p chr5 149732867 149732888 + hsa-miR-137-3p chr1 98046091 98046113 - hsa-miR-28-5p chr3 188688794 188688815 + hsa-miR-552-3p chr1 34669614 34669634 - hsa-miR-3681-3p chr2 12199174 12199195 + hsa-miR-892c-3p chrX 145992760 145992781 - hsa-miR-1252-5p chr12 79419261 79419282 + hsa-miR-514b-5p chrX 147250197 147250218 - hsa-miR-1323 chr19 53671978 53671999 + hsa-miR-126-5p chr9 136670616 136670636 + hsa-miR-429 chr1 1169055 1169076 + hsa-miR-4524b-5p chr17 69099570 69099590 + hsa-miR-1270 chr19 20399320 20399342 - hsa-miR-32-5p chr9 109046272 109046293 - hsa-miR-378h chr5 154829466 154829486 + hsa-miR-448 chrX 114823524 114823545 + hsa-miR-29a-3p chr7 130876748 130876769 - hsa-miR-378i chr22 41923271 41923291 - hsa-miR-218-5p chr5 168768211 168768231 - hsa-miR-135a-5p chr12 97563834 97563856 + hsa-miR-217-5p chr2 55983020 55983042 - hsa-miR-548o-3p chr20 38516607 38516628 + hsa-miR-340-5p chr5 180015361 180015382 - hsa-miR-4524a-5p chr17 69099606 69099627 - hsa-miR-374b-3p chrX 74218557 74218578 - hsa-miR-422a chr15 63870989 63871010 - hsa-miR-579-3p chr5 32394392 32394414 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC079781.5 chr7 97851688 97972985 - AC106864.1 chr4 112693047 112706810 - AC108860.2 chr8 94637285 94639467 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: GSE125442 Sample Source: Urine Source Fraction: Exosome Platform: GPL21290 Method: NGS Num of detected RNA Type: 1 Num of detected RNAs of this Type: 882 Sample treatment protocol: Exosomes were isolated by ultracentrifugation from 50-ml urine samples. RNA Extract protocol: A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol. RNA library preparation protocol: Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA