exRNAdisease

Entry Detail

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General Information

Database ID: exR0410634 RNA Name: SNHG1 RNA Type: lncRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 62851984 End Site(bp): 62855953 External Links: ENSG00000255717

Disease Information

Disease Name: Clear Cell Renal Cell Carcinoma Disease Category: Cancers MeSH ID: D002292 Type: Neoplasms/Urogenital Neoplasms Alias: Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID: GSE125442 Description: Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma Experimental Design: Cancer vs Control Case Disease Type: Clear Cell Renal Cell Carcinoma Case Disease SubType: NA Case Sample: Clear Cell Renal Cell Carcinoma Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD18 chr4 127965306 128039927 + AC104109.3 chr5 134167170 134226071 - ACBD5 chr10 27195214 27242130 - AFG3L2 chr18 12328944 12377227 - AGK chr7 141551278 141655244 + AKR1A1 chr1 45550543 45570049 + AL121594.1 chr14 35122549 35317474 + AL132780.3 chr14 22946270 22982258 - AL136454.1 chr1 192716132 192716653 + AL139011.2 chr1 160216800 160285130 - AATF chr17 36948954 37056871 + AD000671.2 chr19 35739252 35745432 - ADA chr20 44619522 44652233 - AKT3 chr1 243488233 243851079 - AL353588.1 chr6 44273194 44378957 + AL365205.1 chr6 41780349 41790141 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3163 chr11 66934476 66934497 - hsa-miR-361-3p chrX 85903641 85903663 - hsa-miR-7151-5p chr10 67403388 67403410 - hsa-miR-670-3p chr11 43559714 43559734 + hsa-miR-3918 chr6 158764715 158764735 - hsa-miR-3179 chr16 18411905 18411926 - hsa-miR-577 chr4 114656774 114656794 + hsa-miR-181b-5p chr9 124693725 124693747 + hsa-miR-556-5p chr1 162342561 162342582 + hsa-miR-2278 chr9 94809977 94809998 + hsa-miR-18a-5p chr13 91350756 91350778 + hsa-miR-450b-5p chrX 134540231 134540252 - hsa-miR-590-5p chr7 74191213 74191234 + hsa-miR-1276 chr15 85770548 85770567 - hsa-miR-101-3p chr1 65058442 65058462 - hsa-miR-376b-3p chr14 101040497 101040518 + hsa-miR-181c-5p chr19 13874725 13874746 + hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-421 chrX 74218392 74218414 - hsa-miR-760 chr1 93846880 93846899 + hsa-miR-2115-3p chr3 48316381 48316402 - hsa-miR-320a-3p chr8 22244975 22244996 - hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-154-5p chr14 101059769 101059790 + hsa-miR-182-5p chr7 129770447 129770470 - hsa-miR-345-3p chr14 100307912 100307933 + hsa-miR-488-3p chr1 177029374 177029394 - hsa-miR-409-5p chr14 101065314 101065336 + hsa-miR-2355-3p chr2 207109999 207110020 - hsa-miR-3127-5p chr2 96798288 96798310 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC023509.1 chr12 53441741 53467528 + AC097478.1 chr4 89743792 89744305 + AC145207.5 chr17 81878425 81881106 - AC242842.1 chr1 149607765 149612402 + AL022311.1 chr22 37876148 37895563 + AL132780.1 chr14 22929607 22956374 + Display:

Experiment Detail

GEO ID: GSE125442 Sample Source: Urine Source Fraction: Exosome Platform: GPL21290 Method: NGS Num of detected RNA Type: 1 Num of detected RNAs of this Type: 882 Sample treatment protocol: Exosomes were isolated by ultracentrifugation from 50-ml urine samples. RNA Extract protocol: A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol. RNA library preparation protocol: Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA