exRNAdisease

Entry Detail

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General Information

Database ID: exR0410640 RNA Name: SNHG3 RNA Type: lncRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 28505980 End Site(bp): 28510892 External Links: ENSG00000242125

Disease Information

Disease Name: Clear Cell Renal Cell Carcinoma Disease Category: Cancers MeSH ID: D002292 Type: Neoplasms/Urogenital Neoplasms Alias: Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID: GSE125442 Description: Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma Experimental Design: Cancer vs Control Case Disease Type: Clear Cell Renal Cell Carcinoma Case Disease SubType: NA Case Sample: Clear Cell Renal Cell Carcinoma Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004922.1 chr7 99325879 99394653 + AC007192.1 chr19 18153158 18178117 + AC011448.1 chr19 19516227 19536076 + AC124312.1 chr15 24955034 25000276 + ACAP1 chr17 7336529 7351477 + ACTG1 chr17 81509971 81523847 - AEN chr15 88621337 88632281 + AGRN chr1 1020120 1056118 + AK6 chr5 69350984 69370013 - AKR1A1 chr1 45550543 45570049 + AL513165.2 chr9 37512547 37592469 - ALDH1B1 chr9 38392702 38398661 + AC024592.3 chr19 5866171 5903787 - AC026954.2 chr17 7312661 7319174 - AC107871.1 chr15 68184032 68229718 - AIMP1 chr4 106315544 106349456 + AL022318.4 chr22 39014363 39033276 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-196a-5p chr17 48632532 48632553 - hsa-miR-186-5p chr1 71067681 71067702 - hsa-miR-326 chr11 75335108 75335127 - hsa-miR-384 chrX 76919285 76919304 - hsa-miR-485-5p chr14 101055427 101055448 + hsa-miR-493-5p chr14 100869075 100869096 + hsa-miR-515-5p chr19 53685022 53685045 + hsa-miR-519e-5p chr19 53679953 53679974 + hsa-miR-330-5p chr19 45639049 45639070 - hsa-miR-2681-3p chr13 101967665 101967686 - hsa-miR-2355-5p chr2 207110043 207110063 - hsa-miR-3614-5p chr17 56891319 56891341 - hsa-miR-3940-3p chr19 6416434 6416455 - hsa-miR-499b-5p chr20 34990443 34990463 - hsa-miR-5094 chr15 89850690 89850711 - hsa-miR-514a-5p chrX 147284690 147284712 - hsa-miR-6509-5p chr7 135207044 135207064 - hsa-miR-6512-3p chr2 177313811 177313832 - hsa-miR-412-5p chr14 101065465 101065487 + hsa-miR-6720-5p chr6 1390359 1390381 - hsa-miR-6884-5p chr17 40026383 40026404 - hsa-miR-5100 chr10 42997630 42997651 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004069.1 chr4 105137280 105140619 - AC011825.3 chr18 32018829 32111779 + AC023509.1 chr12 53441741 53467528 + AC099778.1 chr3 47379089 47380999 - AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: GSE125442 Sample Source: Urine Source Fraction: Exosome Platform: GPL21290 Method: NGS Num of detected RNA Type: 1 Num of detected RNAs of this Type: 882 Sample treatment protocol: Exosomes were isolated by ultracentrifugation from 50-ml urine samples. RNA Extract protocol: A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol. RNA library preparation protocol: Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA