exRNAdisease

General Information

Database ID:

exR0410645

RNA Name:

SNHG8

RNA Type:

lncRNA

Chromosome:

chr4

Starnd:

Coordinate:

Start Site(bp):

118278709

End Site(bp):

118285316

External Links:

Disease Information

Disease Name:	Clear Cell Renal Cell Carcinoma
Disease Category:	Cancers
MeSH ID:	D002292
Type:	Neoplasms/Urogenital Neoplasms
Alias:	Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID:	GSE125442
Description:	Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma
Experimental Design:	Cancer vs Control
Case Disease Type:	Clear Cell Renal Cell Carcinoma
Case Disease SubType:	NA
Case Sample:	Clear Cell Renal Cell Carcinoma
Control Sample:	Healthy
Number of Case:	10
Number of Control:	10
Number of Samples:	20

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC048338.1	chr12	122207779	122266423	-
ACTB	chr7	5527148	5563784	-
ACTG1	chr17	81509971	81523847	-
AFG1L	chr6	108294991	108526796	+
ALDOA	chr16	30064164	30070457	+
AC024592.3	chr19	5866171	5903787	-

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-149-5p	chr2	240456015	240456037	+
hsa-miR-154-5p	chr14	101059769	101059790	+
hsa-miR-384	chrX	76919285	76919304	-
hsa-miR-494-3p	chr14	101029681	101029702	+
hsa-miR-522-3p	chr19	53751264	53751285	+
hsa-miR-588	chr6	126484646	126484666	+
hsa-miR-620	chr12	116148575	116148594	-
hsa-miR-411-5p	chr14	101023340	101023360	+
hsa-miR-656-3p	chr14	101066766	101066786	+
hsa-miR-542-3p	chrX	134541364	134541385	-
hsa-miR-425-5p	chr3	49020199	49020221	-
hsa-miR-371a-5p	chr19	53787680	53787699	+
hsa-miR-1270	chr19	20399320	20399342	-
hsa-miR-224-3p	chrX	151958584	151958606	-
hsa-miR-4701-5p	chr12	48772014	48772035	-
hsa-miR-506-5p	chrX	147230788	147230809	-
hsa-miR-873-3p	chr9	28888889	28888910	-
hsa-miR-7151-5p	chr10	67403388	67403410	-

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC007952.4	chr17	19112000	19112636	-
AC068205.2	chr11	43578889	43840030	+
AC139149.1	chr17	81514047	81527776	+
AL133215.2	chr10	101060029	101061005	-

Display:

Experiment Detail

GEO ID:	GSE125442
Sample Source:	Urine
Source Fraction:	Exosome
Platform:	GPL21290
Method:	NGS
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	882
Sample treatment protocol:	Exosomes were isolated by ultracentrifugation from 50-ml urine samples.
RNA Extract protocol:	A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol.
RNA library preparation protocol:	Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference