exRNAdisease

Entry Detail

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General Information

Database ID: exR0410717 RNA Name: TUG1 RNA Type: lncRNA Chromosome: chr22 Starnd: + Coordinate: Start Site(bp): 30969245 End Site(bp): 30979395 External Links: ENSG00000253352

Disease Information

Disease Name: Clear Cell Renal Cell Carcinoma Disease Category: Cancers MeSH ID: D002292 Type: Neoplasms/Urogenital Neoplasms Alias: Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID: GSE125442 Description: Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma Experimental Design: Cancer vs Control Case Disease Type: Clear Cell Renal Cell Carcinoma Case Disease SubType: NA Case Sample: Clear Cell Renal Cell Carcinoma Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005258.1 chr19 2269525 2341172 + ACOT7 chr1 6264269 6394391 - ADNP chr20 50888916 50931437 - AGO1 chr1 35869808 35930532 + AC090004.1 chr3 14135217 14148252 + ADH5 chr4 99070978 99088801 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-590-5p chr7 74191213 74191234 + hsa-miR-3681-3p chr2 12199174 12199195 + hsa-miR-7151-5p chr10 67403388 67403410 - hsa-miR-216a-3p chr2 55988981 55989002 - hsa-miR-9-3p chr15 89368071 89368092 + hsa-miR-362-5p chrX 50008968 50008991 + hsa-miR-299-3p chr14 101023832 101023853 + hsa-miR-145-5p chr5 149430661 149430683 + hsa-miR-4465 chr6 140683855 140683876 + hsa-miR-500b-5p chrX 50010682 50010699 + hsa-miR-4766-5p chr22 40813927 40813947 - hsa-miR-1294 chr5 154347153 154347174 + hsa-miR-425-5p chr3 49020199 49020221 - hsa-miR-495-3p chr14 101033804 101033825 + hsa-miR-499b-5p chr20 34990443 34990463 - hsa-miR-519e-5p chr19 53679953 53679974 + hsa-miR-3129-5p chr2 189133082 189133103 - hsa-miR-1277-5p chrX 118386401 118386424 + hsa-miR-153-3p chr2 219294126 219294147 - hsa-miR-509-3p chrX 147258775 147258796 - hsa-miR-9-5p chr5 88666902 88666924 - hsa-miR-511-3p chr10 17845160 17845179 + hsa-miR-382-5p chr14 101054316 101054337 + hsa-miR-542-3p chrX 134541364 134541385 - hsa-miR-27b-3p chr9 95085505 95085525 + hsa-miR-1343-3p chr11 34941888 34941909 + hsa-miR-221-3p chrX 45746180 45746202 - hsa-miR-376a-3p chr14 101040825 101040845 + hsa-miR-561-5p chr2 188297517 188297538 + hsa-miR-196b-5p chr7 27169528 27169549 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AL021707.1 chr22 38739003 38749041 + Display:

Experiment Detail

GEO ID: GSE125442 Sample Source: Urine Source Fraction: Exosome Platform: GPL21290 Method: NGS Num of detected RNA Type: 1 Num of detected RNAs of this Type: 882 Sample treatment protocol: Exosomes were isolated by ultracentrifugation from 50-ml urine samples. RNA Extract protocol: A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol. RNA library preparation protocol: Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA