exRNAdisease

Entry Detail

---



General Information

Database ID: exR0410745 RNA Name: ZFAS1 RNA Type: lncRNA Chromosome: chr20 Starnd: + Coordinate: Start Site(bp): 49278178 End Site(bp): 49299600 External Links: ENSG00000177410

Disease Information

Disease Name: Clear Cell Renal Cell Carcinoma Disease Category: Cancers MeSH ID: D002292 Type: Neoplasms/Urogenital Neoplasms Alias: Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID: GSE125442 Description: Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma Experimental Design: Cancer vs Control Case Disease Type: Clear Cell Renal Cell Carcinoma Case Disease SubType: NA Case Sample: Clear Cell Renal Cell Carcinoma Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD14B chr3 51968510 51983409 - AC138811.2 chr16 18788063 18801519 - ACTG1 chr17 81509971 81523847 - AEN chr15 88621337 88632281 + AC107871.1 chr15 68184032 68229718 - AC134669.1 chr17 31305213 31318831 - AGTPBP1 chr9 85546539 85742029 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-96-5p chr7 129774739 129774761 - hsa-miR-7-5p chr19 4770700 4770723 + hsa-miR-150-5p chr19 49500832 49500853 - hsa-miR-193a-3p chr17 31560050 31560071 + hsa-miR-34b-5p chr11 111512950 111512972 + hsa-miR-432-5p chr14 100884496 100884518 + hsa-miR-193b-3p chr16 14304017 14304038 + hsa-miR-520a-5p chr19 53690895 53690915 + hsa-miR-525-5p chr19 53697547 53697567 + hsa-miR-510-5p chrX 147272378 147272399 - hsa-miR-642a-5p chr19 45674943 45674964 + hsa-miR-421 chrX 74218392 74218414 - hsa-miR-582-3p chr5 59703630 59703651 - hsa-miR-654-3p chr14 101040269 101040290 + hsa-miR-1323 chr19 53671978 53671999 + hsa-miR-1271-5p chr5 176367960 176367981 + hsa-miR-548o-3p chr20 38516607 38516628 + hsa-miR-449c-5p chr5 55172313 55172337 - hsa-miR-2682-5p chr1 98045307 98045329 - hsa-miR-3121-3p chr1 180438323 180438344 - hsa-miR-3924 chr10 57304489 57304510 - hsa-miR-3942-5p chr15 35372321 35372342 - hsa-miR-4640-3p chr6 30890949 30890970 + hsa-miR-4703-5p chr13 51552599 51552621 + hsa-miR-5047 chr17 64501230 64501250 - hsa-miR-6835-3p chr6 34240714 34240736 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC139149.1 chr17 81514047 81527776 + AC147651.4 chr7 603185 608482 + AC245014.3 chr1 145281116 145281462 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: GSE125442 Sample Source: Urine Source Fraction: Exosome Platform: GPL21290 Method: NGS Num of detected RNA Type: 1 Num of detected RNAs of this Type: 882 Sample treatment protocol: Exosomes were isolated by ultracentrifugation from 50-ml urine samples. RNA Extract protocol: A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol. RNA library preparation protocol: Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA