exRNAdisease

Entry Detail

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General Information

Database ID: exR0428554 RNA Name: A1BG RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 58345178 End Site(bp): 58353492 External Links: ENSG00000121410

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTR8 chr3 53867066 53882152 - AKT1 chr14 104769349 104795751 - ARMC5 chr16 31458080 31467166 + C2orf49 chr2 105337532 105349211 + CCT7 chr2 73233420 73253021 + CD70 chr19 6583183 6604103 - GAPDH chr12 6534512 6538374 + PBX2 chr6 32184733 32190202 - PGM1 chr1 63593411 63660245 + PREX1 chr20 48624252 48827999 - RNF135 chr17 30970984 30999911 + RPL19 chr17 39200283 39204732 + RPL37 chr5 40825262 40835222 - SRP14 chr15 40035690 40039181 - TMSB10 chr2 84905656 84906671 + UNC45A chr15 90930180 90954093 + WDR18 chr19 984271 998438 + WDR6 chr3 49007062 49015953 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012313.3 chr19 58346854 58362751 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.