exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428561 RNA Name: AADAT RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 170060222 End Site(bp): 170091699 External Links: ENSG00000109576

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ARL4C chr2 234493041 234497081 - B3GALNT2 chr1 235447190 235504452 - CPD chr17 30378927 30469989 + EP400 chr12 131949942 132080460 + FOXF2 chr6 1389576 1395603 + FXR1 chr3 180868141 180982753 + GNAS chr20 58839718 58911192 + HOXA1 chr7 27093313 27095996 - LRP8 chr1 53242364 53328469 - MACF1 chr1 39081316 39487177 + NCSTN chr1 160343316 160358952 + NDUFB3 chr2 201071433 201085750 + PGS1 chr17 78378649 78425114 + PSMD3 chr17 39980807 39997959 + RABL6 chr9 136807943 136841187 + ZNF43 chr19 21804949 21852125 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-497-5p chr17 7017979 7017999 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL355987.4 chr9 136799223 136810042 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.