exRNAdisease

Entry Detail

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General Information

Database ID: exR0428565 RNA Name: AAMP RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 218264123 End Site(bp): 218270257 External Links: ENSG00000127837

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANKRD40 chr17 50693198 50707914 - MOB1A chr2 74152528 74178898 - SF3A2 chr19 2236824 2248655 + HSP90AA1 chr14 102080738 102139699 - HSP90AB1 chr6 44246166 44253888 + RPL10A chr6 35468401 35470785 + BOD1 chr5 173607145 173616659 - FUS chr16 31180110 31194871 + RBMX chrX 136848004 136880764 - ELAC2 chr17 12991612 13018065 - SF3B4 chr1 149923317 149927803 - PLXNA1 chr3 126988594 127037392 + IPO7 chr11 9384652 9448127 + RABGAP1 chr9 122940833 123104866 + NFKBIL1 chr6 31546870 31558829 + MAP7D1 chr1 36155579 36180849 + ANKH chr5 14704800 14871778 - KHDC4 chr1 155913045 155934413 - SPSB4 chr3 141051347 141148611 + WDR75 chr2 189441446 189475552 + ACTB chr7 5527148 5563784 - NT5DC2 chr3 52524385 52535054 - ITPR1 chr3 4493345 4847840 + DHRS11 chr17 36591879 36600804 + CRTAP chr3 33114014 33147773 + CCNG1 chr5 163437569 163446151 + EEF1D chr8 143579697 143599541 - SOX2 chr3 181711925 181714436 + XAB2 chr19 7619525 7629545 - AGPAT5 chr8 6708642 6761503 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC073046.1 chr2 73985132 73986343 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + ARRDC1-AS1 chr9 137615332 137618906 - BX284668.2 chr1 16870945 16883659 + LINC01578 chr15 92819540 92899701 + NEAT1 chr11 65422774 65445540 + SNHG25 chr17 64145970 64146476 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.