exRNAdisease

Entry Detail

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General Information

Database ID: exR0428571 RNA Name: AASDH RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 56338287 End Site(bp): 56387508 External Links: ENSG00000157426

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CANT1 chr17 78991716 79009867 - EMC7 chr15 34084017 34101862 - EPN1 chr19 55675226 55709858 + GAPDH chr12 6534512 6538374 + GK3P chr4 165277812 165279679 - GOLPH3 chr5 32124716 32174319 - HMGCR chr5 75336329 75362101 + HOXB1 chr17 48528526 48531011 - LARP6 chr15 70829130 70854157 - MAST3 chr19 18097793 18151692 + MGST1 chr12 16347142 16609259 + MTHFD2 chr2 74198610 74217565 + MTRNR2L12 chr3 96617188 96618236 - NDUFS5 chr1 39026318 39034636 + PIP5K1A chr1 151197949 151249536 + PLCXD1 chrX 276322 303356 + RBFOX2 chr22 35738736 36028824 - RER1 chr1 2391775 2405442 + RPS18 chr6 33272075 33276511 + SLC11A2 chr12 50979401 51028566 - SPAG9 chr17 50962174 51120868 - TFPI chr2 187464230 187565760 - TPP1 chr11 6612768 6619448 - UBE2I chr16 1308880 1327018 + UGP2 chr2 63840940 63891562 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012485.1 chr2 238231684 238255633 + NAALADL2-AS2 chr3 175234861 175271096 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.