exRNAdisease

Entry Detail

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General Information

Database ID: exR0428572 RNA Name: AASDHPPT RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 106075501 End Site(bp): 106098699 External Links: ENSG00000149313

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand GTF2F2 chr13 45120510 45284893 + CFL1 chr11 65823022 65862026 - NUP93 chr16 56730118 56850286 + HSD17B8 chr6 33204655 33206831 + RPL3 chr22 39312882 39320389 - RASSF3 chr12 64507001 64697564 + TMBIM6 chr12 49707725 49764934 + HNRNPL chr19 38836388 38852347 - CXXC4 chr4 104468308 104494901 - PSME3 chr17 42824385 42843760 + AHCY chr20 34280268 34311802 - ESRP1 chr8 94641074 94707466 + AKAP10 chr17 19904302 19978343 - PCLAF chr15 64364304 64387687 - COA3 chr17 42795147 42798704 - MTA2 chr11 62593214 62601865 - EIF4G2 chr11 10797050 10808940 - WDR73 chr15 84639281 84654343 - PUM2 chr2 20248691 20352234 - GTPBP6 chrX 304529 318819 - NAP1L4 chr11 2944431 2992377 - MATR3 chr5 139273752 139331671 + IRF7 chr11 612553 615983 - SINHCAF chr12 31280584 31327058 - RAB8A chr19 16111889 16134234 + SPG21 chr15 64963022 64990310 - PANK3 chr5 168548495 168579368 - DIAPH1 chr5 141515016 141619055 - RPS29 chr14 49570984 49599164 - HMGA1 chr6 34236873 34246231 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC064807.1 chr8 51899268 51949874 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.