exRNAdisease

Entry Detail

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General Information

Database ID: exR0428576 RNA Name: ABAT RNA Type: mRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 8674596 End Site(bp): 8784575 External Links: ENSG00000183044

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ARFIP2 chr11 6474683 6481479 - BTNL9 chr5 181040225 181061521 + ESRP1 chr8 94641074 94707466 + HNRNPA1P48 chr16 51553436 51647132 + LSM14B chr20 62122461 62135374 + MEA1 chr6 43011143 43016868 - PTCD2 chr5 72320367 72368395 + RHBDF2 chr17 76470891 76501790 - RPS28 chr19 8321158 8323340 + RPS6 chr9 19375715 19380236 - SENP6 chr6 75601509 75718281 + SNRPD2 chr19 45687454 45692569 - SP2 chr17 47896150 47928957 + SPTLC1 chr9 92000087 92115413 - TMEM9 chr1 201134772 201171574 - USP7 chr16 8892097 8975328 - ZBTB11 chr3 101648889 101677132 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-485-5p chr14 101055427 101055448 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand ALDH1L1-AS2 chr3 126180012 126210169 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.