exRNAdisease

Entry Detail

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General Information

Database ID: exR0428577 RNA Name: ABCA1 RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 104781006 End Site(bp): 104928155 External Links: ENSG00000165029

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand COX5B chr2 97646062 97648383 + EIF3L chr22 37848868 37889407 + EWSR1 chr22 29268009 29300525 + FEN1 chr11 61792911 61797238 + GANAB chr11 62624826 62646726 - GAPDH chr12 6534512 6538374 + HADH chr4 107989714 108035175 + IGF2 chr11 2129112 2141238 - IGF2BP3 chr7 23310209 23470491 - KDM3B chr5 138352685 138437028 + LSMEM1 chr7 112480853 112491062 + LUC7L3 chr17 50719565 50756219 + MPI chr15 74890005 74902219 + NISCH chr3 52455118 52493068 + PIANP chr12 6693792 6700800 - PPRC1 chr10 102132994 102150333 + RPL13A chr19 49487554 49492308 + RPL14 chr3 40457292 40468587 + RPL19 chr17 39200283 39204732 + RPS23 chr5 82273320 82278396 - SEC11A chr15 84669538 84716460 - SHROOM3 chr4 76435229 76783253 + SND1 chr7 127652194 128092609 + UBE2R2 chr9 33817160 33920399 + ZNF217 chr20 53567065 53609907 - ZNF568 chr19 36916329 36998700 + ZNF696 chr8 143289676 143299952 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1294 chr5 154347153 154347174 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.