exRNAdisease

Entry Detail

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General Information

Database ID: exR0428582 RNA Name: ABCA3 RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 2275881 End Site(bp): 2340746 External Links: ENSG00000167972

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ATG2B chr14 96279195 96363341 - BCAR1 chr16 75228181 75268053 - LAMB2 chr3 49121114 49133118 - HLA-F chr6 29722775 29738528 + NOC4L chr12 132144457 132152473 + HS3ST3A1 chr17 13494032 13601929 - ASRGL1 chr11 62337448 62393412 + HNRNPUL2-BSCL2 chr11 62690275 62727384 - SIK3 chr11 116843402 117098437 - MCMBP chr10 119829404 119892556 - CYB5R3 chr22 42617840 42649392 - RPL11 chr1 23691742 23696835 + KLHL21 chr1 6590724 6614607 - PVRIG chr7 100218241 100221490 + ZNF219 chr14 21090077 21104722 - PKM chr15 72199029 72231822 - HMGB2 chr4 173331376 173334432 - DNAJC18 chr5 139408588 139444491 - MT-ND4L chrMT 10470 10766 + CHTF18 chr16 788046 800737 + CDH4 chr20 61252261 61940617 + TSC2 chr16 2047967 2089491 + CDCA2 chr8 25459199 25507911 + TPRN chr9 137191617 137204193 - HLA-E chr6 30489509 30494194 + DCP2 chr5 112976702 113022195 + FAM104A chr17 73207353 73236753 - BUB3 chr10 123154402 123170467 + RFWD3 chr16 74621399 74666877 - TUBB2A chr6 3153666 3157544 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC022167.2 chr16 8848105 8860456 + AC245014.3 chr1 145281116 145281462 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.