exRNAdisease

Entry Detail

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General Information

Database ID: exR0428594 RNA Name: ABCB8 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 151028422 End Site(bp): 151047782 External Links: ENSG00000197150

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand USP20 chr9 129834698 129881838 + RANBP1 chr22 20115938 20127355 + BAG6 chr6 31639028 31652705 - FKRP chr19 46746046 46776988 + SOX2 chr3 181711925 181714436 + KPNA4 chr3 160495007 160565571 - ATP6AP1 chrX 154428645 154436516 + THRA chr17 40058290 40093867 + PTK7 chr6 43076307 43161719 + FAM107B chr10 14518557 14774897 - TRMT2A chr22 20111875 20117392 - AC068946.2 chr2 219209772 219222738 - YIF1B chr19 38303558 38317273 - FLOT1 chr6 30727709 30742732 - HSPA1B chr6 31827738 31830254 + DVL3 chr3 184155377 184173614 + EME2 chr16 1772810 1781708 + OAZ1 chr19 2269509 2273490 + SLC37A4 chr11 119024114 119030906 - DDB1 chr11 61299451 61342596 - LAMB2 chr3 49121114 49133118 - SLC19A1 chr21 45493572 45573365 - NKRF chrX 119588337 119606443 - LOXL1 chr15 73925989 73952137 + TMBIM1 chr2 218274197 218292586 - APBB1 chr11 6395124 6419414 - ADNP2 chr18 80109262 80147523 + AFF4 chr5 132875395 132963634 - SENP3-EIF4A1 chr17 7563287 7578715 + SMG1 chr16 18804853 18926454 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.