exRNAdisease

Entry Detail

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General Information

Database ID: exR0428609 RNA Name: ABCD3 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 94418389 End Site(bp): 94518666 External Links: ENSG00000117528

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SLC25A6 chrX 1386152 1392113 - RPL13 chr16 89560657 89566828 + ACYP2 chr2 53970838 54305300 + RPL15 chr3 23916545 23924374 + C18orf25 chr18 46173553 46266992 + GFM1 chr3 158644278 158692575 + SH3KBP1 chrX 19533977 19887600 - EGLN2 chr19 40798996 40808434 + MIF chr22 23894383 23895227 + LTA4H chr12 96000753 96043520 - RIC1 chr9 5629025 5776557 + EIF3L chr22 37848868 37889407 + SMIM13 chr6 11093834 11138733 + ZKSCAN8 chr6 28141883 28159460 + NACA chr12 56712427 56731628 - CBX4 chr17 79833156 79839440 - RPS6 chr9 19375715 19380236 - HNRNPR chr1 23303771 23344336 - RPL28 chr19 55385345 55403250 + MYCN chr2 15940550 15947007 + PELP1 chr17 4669774 4704337 - HSP90AA1 chr14 102080738 102139699 - GMPS chr3 155870650 155944020 + COPA chr1 160288594 160343273 - PLEKHO2 chr15 64841883 64868002 + MAP2K4 chr17 12020829 12143830 + LAPTM4B chr8 97775057 97853013 + RBX1 chr22 40951347 40973309 + C11orf24 chr11 68261338 68272001 - CRYL1 chr13 20403666 20525873 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL022311.1 chr22 37876148 37895563 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.