exRNAdisease

Entry Detail

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General Information

Database ID: exR0428610 RNA Name: ABCD4 RNA Type: mRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 74285269 End Site(bp): 74303055 External Links: ENSG00000119688

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand QSER1 chr11 32892820 32993316 + MRPL46 chr15 88459477 88467390 - MXRA8 chr1 1352689 1361777 - NSUN2 chr5 6599239 6633291 - M6PR chr12 8940361 8949761 - SIK1 chr21 43414483 43427131 - RPL10 chrX 154389955 154409168 + SFI1 chr22 31488688 31618588 + C5orf24 chr5 134845680 134859735 + RDH13 chr19 55039108 55071291 - CRYL1 chr13 20403666 20525873 - LONRF3 chrX 118974614 119018355 + ORC3 chr6 87590067 87667453 + ACOT8 chr20 45841721 45857405 - TP53RK chr20 46684365 46689444 - ZNF668 chr16 31060843 31074240 - PFN1 chr17 4945652 4949061 - LTK chr15 41503637 41513887 - TOMM40L chr1 161225939 161230746 + FBXW4 chr10 101610664 101695295 - NEO1 chr15 73051710 73305205 + SELENOS chr15 101270817 101277500 - NHP2 chr5 178149460 178153967 - EIF4H chr7 74174245 74197101 + HSP90AB1 chr6 44246166 44253888 + BTBD2 chr19 1985438 2034881 - TRIP13 chr5 892884 919357 + HSPA4 chr5 133052013 133106449 + CCDC167 chr6 37482938 37499893 - VMP1 chr17 59707192 59842255 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005519.1 chr14 74289127 74294425 - AC005562.1 chr17 30576464 30672789 + AC007952.4 chr17 19112000 19112636 - AC011476.2 chr19 55027593 55053928 - MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.