exRNAdisease

Entry Detail

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General Information

Database ID: exR0428611 RNA Name: ABCE1 RNA Type: mRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 145098288 End Site(bp): 145129524 External Links: ENSG00000164163

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MGST1 chr12 16347142 16609259 + MTX2 chr2 176269395 176338025 + RPL37A chr2 216498825 216579180 + FAM162A chr3 122384176 122412334 + ENOPH1 chr4 82430590 82461177 + ANKRD17 chr4 73073376 73258798 - SLC25A29 chr14 100291116 100306547 - INSIG1 chr7 155297776 155310235 + LAMTOR1 chr11 72085895 72103297 - GNB5 chr15 52115105 52191369 - IVNS1ABP chr1 185296388 185317273 - TIMMDC1 chr3 119498547 119525090 + HOXA3 chr7 27106184 27152581 - STMN1 chr1 25884181 25906991 - UGP2 chr2 63840940 63891562 + RPL3 chr22 39312882 39320389 - PGK1 chrX 77910739 78129295 + RBL2 chr16 53433977 53491648 + BCAT1 chr12 24810024 24949101 - RPS23 chr5 82273320 82278396 - TNPO2 chr19 12699194 12724011 - TUBB chr6 30720352 30725426 + CHTF8 chr16 69118010 69132578 - CLPTM1L chr5 1317752 1345099 - RAB10 chr2 26034084 26137454 + MDH2 chr7 76048051 76067508 + CREBZF chr11 85659708 85682908 - C19orf48 chr19 50797704 50804929 - EWSR1 chr22 29268009 29300525 + ATP5MG chr11 118401606 118431496 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL157871.6 chr14 100279959 100291456 - FAM215B chr17 46558830 46562795 - MAPKAPK5-AS1 chr12 111839764 111842902 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.