exRNAdisease

Entry Detail

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General Information

Database ID: exR0428630 RNA Name: ABHD17C RNA Type: mRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 80679684 End Site(bp): 80755621 External Links: ENSG00000136379

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand NUB1 chr7 151341699 151378449 + PLEKHG3 chr14 64704102 64750249 + KIAA1671 chr22 24952730 25197448 + TCFL5 chr20 62841005 62861822 - AGPAT1 chr6 32168212 32178096 - EEF2 chr19 3976056 3985463 - MEX3A chr1 156072013 156082465 - MKKS chr20 10401009 10434222 - ANXA2 chr15 60347134 60402883 - BTBD7 chr14 93237550 93333092 - CLTA chr9 36190856 36304781 + CDC37 chr19 10391133 10420121 - FMR1 chrX 147911951 147951125 + ZFHX3 chr16 72782885 73891871 - GJA1 chr6 121435595 121449727 + CLEC2D chr12 9664969 9699553 + NISCH chr3 52455118 52493068 + PRTG chr15 55611544 55743152 - SUZ12 chr17 31937007 32001038 + GNAS chr20 58839718 58911192 + MLLT1 chr19 6210381 6279975 - TRAPPC12 chr2 3379675 3485094 + NARS2 chr11 78435968 78574874 - PAIP1 chr5 43526267 43557758 - NUP93 chr16 56730118 56850286 + AK1 chr9 127866486 127877675 - HM13 chr20 31514410 31577923 + CBX3 chr7 26201162 26213607 + MRPS16 chr10 73248843 73252693 - RBM4B chr11 66664998 66677887 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC079949.1 chr12 127142029 127146532 - AL157935.2 chr9 127934503 127940952 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.