exRNAdisease

Entry Detail

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General Information

Database ID: exR0428631 RNA Name: ABHD18 RNA Type: mRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 127965306 End Site(bp): 128039927 External Links: ENSG00000164074

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ZNF415 chr19 53107879 53133077 - KLHL23 chr2 169694488 169776989 + TMSB4Y chrY 13703899 13706024 + RPL4 chr15 66498015 66524532 - SLITRK4 chrX 143622790 143636101 - ZNF836 chr19 52153864 52171643 - MAPK1 chr22 21754500 21867680 - PCNX1 chr14 70907405 71115382 + LRCH1 chr13 46553168 46753040 + ZNF695 chr1 246945547 247008093 - ZNF595 chr4 53286 88208 + ZNF479 chr7 57119614 57139864 - PAICS chr4 56435741 56464579 + PLCXD1 chrX 276322 303356 + RACK1 chr5 181236897 181248096 - ZNF141 chr4 337814 384868 + SRSF2 chr17 76734115 76737374 - SRSF8 chr11 95067197 95071224 + MCU chr10 72692131 72887694 + ZNF83 chr19 52594060 52690496 - ZNF101 chr19 19668796 19683509 + PSD3 chr8 18527303 19084730 - ARL6IP5 chr3 69084937 69106092 + LIG4 chr13 108207439 108218368 - PLS3 chrX 115561174 115650861 + AGPS chr2 177392757 177559299 + CDCA7L chr7 21900899 21945903 - ZNF732 chr4 270675 305474 - ZNF721 chr4 425815 499156 - ZNF678 chr1 227563543 227677443 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011468.2 chr19 52130548 52171533 - AC067750.1 chr10 86749754 86756298 - SNHG1 chr11 62851984 62855953 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.