exRNAdisease

Entry Detail

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General Information

Database ID: exR0428634 RNA Name: ABHD4 RNA Type: mRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 22598237 End Site(bp): 22613215 External Links: ENSG00000100439

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FAM219A chr9 34398184 34458570 - RPL32 chr3 12834485 12841582 - ZNF708 chr19 21291160 21329425 - AP2A1 chr19 49766968 49807113 + ARHGEF4 chr2 130836916 131047263 + POLD4 chr11 67350772 67356972 - PITPNC1 chr17 67377281 67697261 + TUBA1A chr12 49184795 49189080 - TRIP6 chr7 100867387 100873454 + AXIN1 chr16 287440 352723 - HAT1 chr2 171922448 171983686 + MYL12A chr18 3247481 3256236 + HNRNPA1 chr12 54280193 54287088 + PSMB8 chr6 32840717 32844679 - MT-CO1 chrMT 5904 7445 + GAPDH chr12 6534512 6538374 + CNPPD1 chr2 219171897 219178106 - DDX1 chr2 15591178 15631111 + HNRNPK chr9 83968083 83980616 - OGT chrX 71533104 71575892 + PUM1 chr1 30931506 31065991 - BTBD2 chr19 1985438 2034881 - PSAP chr10 71816298 71851325 - EWSR1 chr22 29268009 29300525 + EIF6 chr20 35278911 35284985 - KDM5B chr1 202724495 202808487 - CBSL chr21 6444869 6468040 - AL121753.1 chr20 35267885 35280043 - CCT8 chr21 29055805 29073797 - TRPV3 chr17 3510502 3557995 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-31-5p chr9 21512158 21512178 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AGAP1-IT1 chr2 235505751 235507566 + GATA2-AS1 chr3 128489212 128502970 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.