exRNAdisease

Entry Detail

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General Information

Database ID: exR0428636 RNA Name: ABHD6 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 58237532 End Site(bp): 58295693 External Links: ENSG00000163686

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010422.3 chr19 12643831 12648397 - AMY2B chr1 103553815 103579534 + FSTL1 chr3 120392293 120450993 - GSKIP chr14 96363452 96387288 + HLA-B chr6 31269491 31357188 - NDUFA10 chr2 239892450 240025345 - NME2 chr17 51165435 51171747 + PSMD14 chr2 161308425 161411717 + RPL27A chr11 8682788 8714759 + SLC12A8 chr3 125082636 125212864 - SLC25A29 chr14 100291116 100306547 - SMU1 chr9 33041765 33076674 - SRSF5 chr14 69726900 69772005 + SSBP4 chr19 18418864 18434562 + TERF2IP chr16 75647773 75761872 + TICRR chr15 89575469 89631056 + TMED7 chr5 115613210 115632992 - TPI1 chr12 6867119 6870948 + UBR7 chr14 93207241 93229215 + VIM chr10 17228241 17237593 + WIPF1 chr2 174559572 174682916 - ZFAND2B chr2 219195237 219209651 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016598.1 chr5 143489855 143531350 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.