exRNAdisease

Entry Detail

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General Information

Database ID: exR0428637 RNA Name: ABHD8 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 17292131 End Site(bp): 17310236 External Links: ENSG00000127220

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ITM2C chr2 230864639 230879248 + TUBA3C chr13 19173772 19181824 - CAP1 chr1 40040233 40072649 + HOXB5 chr17 48591257 48593961 - RPLP2 chr11 809965 812880 + ARHGEF7 chr13 111114559 111305737 + NAP1L1 chr12 76036585 76084958 - DUSP2 chr2 96143169 96145440 - CHST11 chr12 104455295 104762014 + IGFBP2 chr2 216632828 216664436 + GALNS chr16 88813734 88856970 - RPS19 chr19 41860255 41872925 + PTMS chr12 6765516 6770952 + EMC10 chr19 50476400 50490870 + EIF4G2 chr11 10797050 10808940 - DDX17 chr22 38483438 38507660 - LRRC14 chr8 144517992 144525172 + PTK7 chr6 43076307 43161719 + FSTL1 chr3 120392293 120450993 - DNASE2 chr19 12875209 12881466 - ANXA11 chr10 80150889 80205572 - UCHL1 chr4 41256413 41268455 + S100A10 chr1 151982915 151993859 - CITED4 chr1 40861054 40862363 - DBN1 chr5 177456608 177474401 - PKM chr15 72199029 72231822 - MDK chr11 46380756 46383837 + GALNT17 chr7 71132144 71713600 + ZFP91 chr11 58579063 58621550 + RPS28 chr19 8321158 8323340 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC069281.2 chr7 100572232 100578700 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.