exRNAdisease

Entry Detail

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General Information

Database ID: exR0428649 RNA Name: ABR RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 1003518 End Site(bp): 1229738 External Links: ENSG00000159842

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand LSM4 chr19 18306230 18323274 - SHC3 chr9 89005771 89178818 - PMS1 chr2 189784085 189877629 + ZMYM2 chr13 19958670 20091829 + RPL26 chr17 8377516 8383213 - TROAP chr12 49323236 49331731 + RAB24 chr5 177301198 177303744 - RPAIN chr17 5419641 5432876 + TTYH3 chr7 2631986 2664802 + AC010422.3 chr19 12643831 12648397 - CKM chr19 45306413 45322875 - ANTXR1 chr2 69013178 69249327 + PPDPF chr20 63520765 63522206 + NKD2 chr5 1008802 1038943 + CEP250 chr20 35455164 35519280 + CCZ1 chr7 5898725 5926550 + PAFAH1B1 chr17 2593210 2685615 + FHOD1 chr16 67229387 67247481 - YBX1 chr1 42682418 42703805 + ZNRF3 chr22 28883572 29057488 + RBM4 chr11 66638617 66668374 + RPL4 chr15 66498015 66524532 - BCR chr22 23179704 23318037 + CFLAR chr2 201116154 201176687 + FSCN1 chr7 5592816 5606655 + CDK13 chr7 39950121 40099580 + ACTB chr7 5527148 5563784 - RPL39 chrX 119786504 119791630 - TPT1 chr13 45333471 45341370 - MSH2 chr2 47403067 47663146 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-877-5p chr6 30584332 30584351 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC074183.1 chr7 84939349 84940245 - AC135178.2 chr17 8318088 8318712 - MALAT1 chr11 65497688 65506516 + RMRP chr9 35657751 35658018 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.