exRNAdisease

Entry Detail

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General Information

Database ID: exR0428653 RNA Name: ABRAXAS2 RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 124801819 End Site(bp): 124836667 External Links: ENSG00000165660

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AIF1L chr9 131096476 131123152 + ATP2A2 chr12 110280756 110351093 + ATP5F1A chr18 46080248 46104334 - BEX3 chrX 103376395 103378164 + EDARADD chr1 236348257 236502915 + FAR2 chr12 29149103 29340980 + FNIP1 chr5 131641714 131797063 - FRAS1 chr4 78057323 78544269 + GNG4 chr1 235547685 235650754 - GSTP1 chr11 67583742 67586656 + ID2 chr2 8678845 8684461 + IRAK1 chrX 154010506 154019902 - KCNK5 chr6 39188971 39229475 - MSH6 chr2 47695530 47810101 + NAA10 chrX 153929225 153935080 - PLEKHA1 chr10 122374696 122442602 + POGLUT1 chr3 119468963 119494708 + RHOB chr2 20447074 20449440 + RND1 chr12 48857145 48865870 - RPL18A chr19 17859910 17864153 + RPL7 chr8 73290242 73295789 - SF3B5 chr6 144094884 144095573 - SSRP1 chr11 57325986 57335892 - UQCRH chr1 46303698 46316776 + VEGFB chr11 64234538 64238793 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC079248.1 chr2 145872209 145931146 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.