exRNAdisease

Entry Detail

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General Information

Database ID: exR0428656 RNA Name: ABTB2 RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 34150987 End Site(bp): 34358010 External Links: ENSG00000166016

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACAA2 chr18 49782164 49813953 - AL136454.1 chr1 192716132 192716653 + ATE1 chr10 121740421 121928801 - CEP104 chr1 3812086 3857214 - CYP4X1 chr1 47023669 47050751 + ECE1 chr1 21217247 21345572 - EEF2 chr19 3976056 3985463 - FAM118A chr22 45308968 45341955 + FASN chr17 82078338 82098294 - GAPDH chr12 6534512 6538374 + ID3 chr1 23557926 23559501 - KRAS chr12 25205246 25250936 - NPAT chr11 108157215 108222638 - PDIA4 chr7 149003062 149028662 - PHC3 chr3 170086732 170181749 - PTTG1IP chr21 44849585 44873903 - RAB1B chr11 66268590 66277492 + RBBP4 chr1 32651142 32686211 + RPL22 chr1 6185020 6209389 - RPS18 chr6 33272075 33276511 + RUSC1 chr1 155320894 155331114 + SERP1 chr3 150541998 150603228 - SHISA5 chr3 48467798 48504826 - SRGN chr10 69088103 69104805 + SRP68 chr17 76038775 76072517 - STAT6 chr12 57095408 57132139 - TBC1D2B chr15 77984036 78077724 - TUBB chr6 30720352 30725426 + TWNK chr10 100987367 100994403 + ZFYVE9 chr1 52142094 52346686 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AP003392.4 chr11 119065263 119065677 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.