exRNAdisease

General Information

Database ID:

exR0428662

RNA Name:

AC004922.1

RNA Type:

mRNA

Chromosome:

chr7

Starnd:

Coordinate:

Start Site(bp):

99325879

End Site(bp):

99394653

External Links:

Disease Information

Disease Name:	Pediatric TB meningitis
Disease Category:	Infections
MeSH ID:	D014390
Type:	Diseases Category/Infections
Alias:	Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID:	GSE122377
Description:	Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:	Disease Sample Source
Case Disease Type:	Pediatric TB meningitis
Case Disease SubType:	NA
Case Sample:	Pediatric TB meningitis
Control Sample:	Lumbar Puncture Cerebrospinal Fluid
Number of Case:	12
Number of Control:	12
Number of Samples:	24

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
FARSA	chr19	12922479	12934037	-
NCAPD2	chr12	6493356	6531955	+
AL928654.3	chr14	105487199	105492267	+
AC139530.2	chr17	81703371	81720539	+
PSMC2	chr7	103344254	103369395	+
UGP2	chr2	63840940	63891562	+
PKM	chr15	72199029	72231822	-
RPS15	chr19	1438358	1440494	+
MEI1	chr22	41699503	41799456	+
RPS19	chr19	41860255	41872925	+
ACTB	chr7	5527148	5563784	-
LRP10	chr14	22871740	22881713	+
HMG20A	chr15	77420412	77485607	+
TM9SF4	chr20	32109714	32167258	+
PCCB	chr3	136250340	136337896	+
ODC1	chr2	10439968	10448327	-
RPS16	chr19	39433137	39435949	-
PPP2R5C	chr14	101761798	101927989	+
YOD1	chr1	207043849	207052980	-
DCTN5	chr16	23641466	23677472	+
TUBB	chr6	30720352	30725426	+
GRHPR	chr9	37422666	37436990	+
FOXN3	chr14	89124871	89619149	-
TUBA1B	chr12	49127782	49131397	-
UBAP2L	chr1	154220179	154271510	+
PLEKHA2	chr8	38901235	38973912	+
LCMT1	chr16	25111731	25178231	+
ATP5MC2	chr12	53632726	53677408	-
MTRNR2L1	chr17	22523111	22524663	+
SMAD5	chr5	136132845	136188747	+

miRNA targets:

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC016876.2	chr17	7581964	7584086	-
AC068790.8	chr12	123973215	124088594	+
BX284668.2	chr1	16870945	16883659	+
HCP5	chr6	31463170	31478936	+
LIMD1-AS1	chr3	45676369	45689200	-
LINC00847	chr5	180830326	180839742	+
LINC00996	chr7	150433654	150448140	+
LINC01600	chr6	2621913	2634619	-
LINC01641	chr1	227393554	227431035	+
LINC01770	chr1	1430539	1434573	-
MIR663AHG	chr20	26167817	26251546	-
PVT1	chr8	127794526	128187101	+
SNHG3	chr1	28505980	28510892	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	31434901
Title:	Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:	Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:	Nat Commun. 2019 Aug 21;10(1):3767.
Description:	Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.