exRNAdisease

Entry Detail

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General Information

Database ID: exR0428666 RNA Name: AC005670.2 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 46923133 End Site(bp): 47049932 External Links: ENSG00000262633

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC048338.1 chr12 122207779 122266423 - AKAP11 chr13 42272152 42323261 + BECN1 chr17 42810134 42833350 - CD74 chr5 150400041 150412929 - CTC1 chr17 8224815 8248056 - GOSR2 chr17 46923075 46975524 + JAGN1 chr3 9890574 9894349 + JUP chr17 41754604 41786931 - LENG8 chr19 54448887 54462037 + LMO4 chr1 87328880 87348923 + LRRC37A chr17 46292733 46337794 + LRRC37A2 chr17 46511511 46555650 + MLXIP chr12 122078756 122147344 + NUDT21 chr16 56429133 56452199 - PLEKHF2 chr8 95133785 95156685 + QPRT chr16 29663279 29698699 + RNF26 chr11 119334527 119337309 + SLC25A36 chr3 140941830 140980995 + VPS33A chr12 122229564 122266494 - ZNF740 chr12 53180704 53195142 + ZNF747 chr16 30530367 30535347 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005332.5 chr17 68133201 68135935 + SNHG7 chr9 136721366 136728184 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.