exRNAdisease

Entry Detail

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General Information

Database ID: exR0428673 RNA Name: AC008763.2 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 7629796 End Site(bp): 7643048 External Links: ENSG00000268400

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPS28 chr19 8321158 8323340 + MICU1 chr10 72367327 72626191 - CDCA8 chr1 37692481 37709719 + CCL22 chr16 57358783 57366189 + NFKB1 chr4 102501331 102617302 + BGLAP chr1 156242184 156243317 + CCDC88B chr11 64340204 64357534 + STAT1 chr2 190908460 191020960 - PKM chr15 72199029 72231822 - MAU2 chr19 19320829 19358754 + STXBP2 chr19 7636881 7647873 + PET100 chr19 7629793 7631956 + LIN28A chr1 26410817 26429728 + MIS12 chr17 5486285 5490814 + RPS26 chr12 56041351 56044697 + ALG2 chr9 99216425 99221942 - ESPL1 chr12 53268299 53293638 + TTC1 chr5 160009113 160065543 + BANP chr16 87949244 88077318 + TMEM170A chr16 75443054 75465497 - SMARCD1 chr12 50085200 50100707 + RGS16 chr1 182598623 182604389 - PMF1-BGLAP chr1 156212982 156243332 + EEF2 chr19 3976056 3985463 - AIF1L chr9 131096476 131123152 + AC068631.3 chr3 186581995 186597103 + AL365205.1 chr6 41780349 41790141 + HDAC5 chr17 44076746 44123702 - ZNF511 chr10 133308914 133313162 + ZNF865 chr19 55605405 55617269 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC087741.1 chr17 80200673 80205949 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.