exRNAdisease

Entry Detail

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General Information

Database ID: exR0428675 RNA Name: AC009690.1 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 72284727 End Site(bp): 72375981 External Links: ENSG00000260729

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC018512.1 chr15 43772617 43799133 - ACTA1 chr1 229431245 229434098 - AP002990.1 chr11 62559603 62591531 - B2M chr15 44711487 44718877 + CAPNS1 chr19 36139953 36150353 + CD52 chr1 26317958 26320523 + EEF1G chr11 62559596 62574086 - EIF6 chr20 35278911 35284985 - ELL3 chr15 43772605 43777315 - EXD2 chr14 69191511 69244020 + HEXA chr15 72340919 72376476 - IVNS1ABP chr1 185296388 185317273 - MIXL1 chr1 226223618 226227054 + MRPL37 chr1 54184041 54225464 + NCL chr2 231453531 231483641 - NFATC3 chr16 68084751 68229259 + PKM chr15 72199029 72231822 - PTMA chr2 231706895 231713541 + RAC3 chr17 82031678 82034204 + RPL13 chr16 89560657 89566828 + RPL37 chr5 40825262 40835222 - RPS16 chr19 39433137 39435949 - THAP7 chr22 20999104 21002196 - TKT chr3 53224712 53256052 - TOR1A chr9 129812942 129824244 - VPS25 chr17 42773449 42779599 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020978.7 chr16 68224713 68227734 + DANCR chr4 52712404 52720351 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.