exRNAdisease

Entry Detail

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General Information

Database ID: exR0428679 RNA Name: AC010422.6 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 12525720 End Site(bp): 12580975 External Links: ENSG00000269693

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CFL1 chr11 65823022 65862026 - DDX21 chr10 68956170 68985068 + DNAJC10 chr2 182716041 182794464 + HLA-DRA chr6 32439878 32445046 + HMGA1 chr6 34236873 34246231 + HSD17B10 chrX 53431258 53434370 - KCTD3 chr1 215567304 215621807 + LSM2 chr6 31797396 31806966 - MORF4L2 chrX 103675496 103688158 - NPLOC4 chr17 81556887 81648465 - PLPP7 chr9 131289459 131359022 + RNPC3 chr1 103525691 103555239 + SHROOM2 chrX 9786429 9949443 + TICAM2 chr5 115578650 115602479 - TMED7-TICAM2 chr5 115578642 115626161 - TPM3 chr1 154155304 154194648 - ZNF101 chr19 19668796 19683509 + ZNF264 chr19 57191500 57222846 + ZNF543 chr19 57320472 57330770 + ZNF544 chr19 58228594 58277495 + ZNF564 chr19 12525373 12551542 - ZNF607 chr19 37696371 37719761 - ZNF627 chr19 11559374 11619161 + ZNF670 chr1 247034637 247078811 - ZNF850 chr19 36714383 36772825 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.