exRNAdisease

Entry Detail

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General Information

Database ID: exR0428696 RNA Name: AC023055.1 RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 55757275 End Site(bp): 55827546 External Links: ENSG00000257390

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FASN chr17 82078338 82098294 - MT-CO3 chrMT 9207 9990 + RPP25L chr9 34610486 34612104 - DUS2 chr16 67987746 68079320 + ETF1 chr5 138506095 138543236 - CCNG1 chr5 163437569 163446151 + METTL16 chr17 2405562 2511891 - RPS18 chr6 33272075 33276511 + RPS29 chr14 49570984 49599164 - HYPK chr15 43796142 43803043 + PSMD12 chr17 67337916 67366605 - UBA52 chr19 18571730 18577550 + SLC39A14 chr8 22367249 22434129 + B2M chr15 44711487 44718877 + NCL chr2 231453531 231483641 - VCL chr10 73995193 74121363 + PLIN2 chr9 19108375 19149290 - NOP56 chr20 2652593 2658393 + KIN chr10 7750962 7787993 - WASF2 chr1 27404230 27490167 - GNAI3 chr1 109548615 109600195 + RPL3 chr22 39312882 39320389 - NUP43 chr6 149724315 149749665 - RPL41 chr12 56116590 56117967 + LDHA chr11 18394560 18408425 + YWHAE chr17 1344275 1400222 - EPB41L2 chr6 130839347 131063322 - AL136454.1 chr1 192716132 192716653 + CMTR2 chr16 71281389 71289715 - CRAT chr9 129094794 129111189 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL096870.2 chr14 24209646 24215987 - AC068831.7 chr15 91022766 91023200 + LINC02035 chr3 122886941 122892416 + MIR22HG chr17 1711493 1717174 - RPARP-AS1 chr10 102449816 102461106 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.