exRNAdisease

Entry Detail

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General Information

Database ID: exR0428711 RNA Name: AC091167.2 RNA Type: mRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 90249556 End Site(bp): 90272208 External Links: ENSG00000261147

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TBX3 chr12 114670255 114684175 - PCDHA9 chr5 140847463 141012344 + RPL13A chr19 49487554 49492308 + SRP9 chr1 225777813 225790468 + DPYSL3 chr5 147390808 147510068 - IPO11 chr5 62403972 62628582 + VCP chr9 35056064 35072627 - RCC2 chr1 17406760 17439677 - DNAJC11 chr1 6634168 6701924 - C14orf132 chr14 96039324 96093889 + IPO5 chr13 97953658 98024296 + RNF4 chr4 2462220 2625320 + CCT5 chr5 10249929 10266389 + EEF2 chr19 3976056 3985463 - ALDOC chr17 28573115 28576948 - FAHD1 chr16 1826941 1840207 + TSPAN33 chr7 129144707 129169699 + CIRBP chr19 1259384 1274880 + ABHD17A chr19 1876810 1885547 - PACS2 chr14 105300563 105398147 + GSPT1 chr16 11868128 11916082 - PCDHA3 chr5 140801028 141012347 + PCDHA7 chr5 140834248 141012347 + L1TD1 chr1 62194849 62212328 + TPI1 chr12 6867119 6870948 + SMN2 chr5 70049612 70078522 + SCARB1 chr12 124776856 124882668 - EIF1 chr17 41688885 41692668 + MRPL30 chr2 99181152 99199561 + NGRN chr15 90265659 90278141 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC021078.1 chr5 149494314 149504670 - LINC00847 chr5 180830326 180839742 + MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.