exRNAdisease

Entry Detail

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General Information

Database ID: exR0428724 RNA Name: AC107871.1 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 68184032 End Site(bp): 68229718 External Links: ENSG00000260007

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANXA7 chr10 73375101 73414076 - JAG2 chr14 105140982 105168824 - ARNTL2 chr12 27332854 27425289 + IPO9 chr1 201829149 201884291 + MTURN chr7 30134986 30162762 + NFKBIA chr14 35401511 35404749 - CAMK2B chr7 44217150 44334577 - DDX17 chr22 38483438 38507660 - F2R chr5 76716126 76735770 + CYTH2 chr19 48469208 48482314 + CBX5 chr12 54230942 54280133 - SHC3 chr9 89005771 89178818 - USP11 chrX 47232866 47248328 + PLOD3 chr7 101205977 101218420 - SRRM2 chr16 2752626 2772538 + FBXO42 chr1 16246840 16352480 - CALML4 chr15 68190705 68206110 - TRMT61A chr14 103529196 103537073 + NCOA5 chr20 46060991 46089962 - ATP5IF1 chr1 28236109 28246906 + IL32 chr16 3065297 3082192 + TACC1 chr8 38728186 38853028 + WWC1 chr5 168291651 168472303 + RAC1 chr7 6374527 6403967 + MDC1 chr6 30699807 30717447 - PDPK1 chr16 2537979 2603188 + PIMREG chr17 6444441 6451469 + PTPN18 chr2 130356045 130375405 + PI4KA chr22 20707691 20859417 - FBXW8 chr12 116910950 117031148 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand BX284668.2 chr1 16870945 16883659 + ERVH48-1 chr21 42916803 42925646 - NEAT1 chr11 65422774 65445540 + SNHG3 chr1 28505980 28510892 + XIST chrX 73820649 73852723 - ZFAS1 chr20 49278178 49299600 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.