exRNAdisease

Entry Detail

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General Information

Database ID: exR0428750 RNA Name: ACADSB RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 123008979 End Site(bp): 123058290 External Links: ENSG00000196177

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand B2M chr15 44711487 44718877 + B4GAT1 chr11 66345374 66347629 - BUB3 chr10 123154402 123170467 + C11orf58 chr11 16613132 16758340 + CCND2 chr12 4273762 4305353 + COX18 chr4 73052362 73069755 - DDX24 chr14 94048287 94081212 - DHCR24 chr1 54849627 54887195 - EIF4E chr4 98871684 98930637 - HLA-B chr6 31269491 31357188 - MCFD2 chr2 46901870 46941855 - MICB chr6 31494881 31511124 + NCOR1 chr17 16029157 16218185 - NFATC3 chr16 68084751 68229259 + NOP53 chr19 47745546 47757058 + POGK chr1 166839447 166856344 + POLE3 chr9 113407235 113410675 - RFFL chr17 35005990 35089319 - TPT1 chr13 45333471 45341370 - VMP1 chr17 59707192 59842255 + YWHAE chr17 1344275 1400222 - YWHAQ chr2 9583967 9630997 - ZNF100 chr19 21722771 21767579 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.