exRNAdisease

Entry Detail

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General Information

Database ID: exR0428754 RNA Name: ACAP2 RNA Type: mRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 195274745 End Site(bp): 195443044 External Links: ENSG00000114331

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SERPINB5 chr18 63476958 63505085 + RPS23 chr5 82273320 82278396 - MTRNR2L12 chr3 96617188 96618236 - KRT8 chr12 52897187 52949954 - TMEM63A chr1 225845536 225882380 - CDCA7L chr7 21900899 21945903 - SSBP4 chr19 18418864 18434562 + RAB34 chr17 28714281 28718429 - ATG4C chr1 62784132 62865516 + MT-ND3 chrMT 10059 10404 + CYFIP2 chr5 157266079 157395595 + DCTN6 chr8 30156319 30183639 + ACAP3 chr1 1292390 1309609 - CREB1 chr2 207529737 207605988 + CLU chr8 27596917 27614700 - COQ4 chr9 128322544 128334072 + ZFR chr5 32354350 32444740 - FLVCR1 chr1 212858275 212899363 + HLA-DRA chr6 32439878 32445046 + ACOT1 chr14 73537143 73543796 + ANAPC15 chr11 72106378 72112780 - SBNO1 chr12 123289109 123364847 - AAK1 chr2 69457997 69674349 - C20orf204 chr20 64034344 64039962 + HSD17B11 chr4 87336515 87391188 - PRKCA chr17 66302613 66810743 + MT-CO3 chrMT 9207 9990 + LCP1 chr13 46125920 46211871 - NRDC chr1 51789191 51878937 - ERP29 chr12 112013348 112023449 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-320a-3p chr8 22244975 22244996 - hsa-miR-320b chr1 224257049 224257070 - hsa-miR-320c chr18 24321716 24321735 + hsa-miR-320d chr13 40727828 40727846 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.