exRNAdisease

Entry Detail

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General Information

Database ID: exR0428758 RNA Name: ACBD3 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 226144679 End Site(bp): 226186741 External Links: ENSG00000182827

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MTRNR2L12 chr3 96617188 96618236 - SLC16A2 chrX 74421493 74533917 + RPS24 chr10 78033760 78056813 + NUSAP1 chr15 41320794 41381050 + LRWD1 chr7 102464956 102473168 + S1PR4 chr19 3172346 3180332 + RSU1 chr10 16590611 16817463 - RPL15 chr3 23916545 23924374 + FOCAD chr9 20658309 20995955 + GPR176 chr15 39799008 39920266 - RAPGEF1 chr9 131576770 131740074 - UTP18 chr17 51260546 51297936 + LIMCH1 chr4 41359607 41700044 + ZNF224 chr19 44094339 44109886 + TTC39C chr18 23992773 24135610 + IGFBP5 chr2 216672105 216695549 - YTHDF1 chr20 63195429 63216139 - RGS10 chr10 119499817 119542719 - CFL1 chr11 65823022 65862026 - TPT1 chr13 45333471 45341370 - RASGRP2 chr11 64726911 64745456 - ACLY chr17 41866917 41930542 - UQCRQ chr5 132866630 132868847 + ID4 chr6 19837370 19842197 + CSNK1E chr22 38290691 38318084 - PUM1 chr1 30931506 31065991 - ZBTB33 chrX 120250752 120258398 + TSN chr2 121737103 121767853 + HK1 chr10 69269984 69401884 + DNPEP chr2 219373527 219400022 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009404.1 chr2 117833937 117841658 + AC023908.2 chr15 39770559 39801333 - AL022311.1 chr22 37876148 37895563 + AL513314.2 chr1 222477252 222504622 - MIR663AHG chr20 26167817 26251546 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.