exRNAdisease

Entry Detail

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General Information

Database ID: exR0428764 RNA Name: ACD RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 67657512 End Site(bp): 67660815 External Links: ENSG00000102977

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DHX9 chr1 182839347 182887982 + DGCR2 chr22 19036282 19122454 - HSP90AB1 chr6 44246166 44253888 + AP002990.1 chr11 62559603 62591531 - ZNF23 chr16 71447597 71463095 - DUSP3 chr17 43766125 43778977 - EEF1G chr11 62559596 62574086 - SEC22C chr3 42547969 42601080 - SLC35B2 chr6 44254096 44257890 - PPM1A chr14 60245752 60299087 + CDK16 chrX 47217860 47229997 + MEPCE chr7 100428790 100434118 + FGFRL1 chr4 1009936 1026898 + NAA10 chrX 153929225 153935080 - MT-CO1 chrMT 5904 7445 + ATP6V1D chr14 67294371 67360265 - EFTUD2 chr17 44849948 44899445 - TFAM chr10 58385345 58399220 + RAF1 chr3 12583601 12664226 - MARCKSL1 chr1 32333839 32336233 - CNOT1 chr16 58519951 58629885 - FSTL3 chr19 676392 683392 + HNRNPD chr4 82352498 82374503 - PCBP2 chr12 53452102 53481162 + TSPAN9 chr12 3077355 3286564 + PSMA4 chr15 78540405 78552417 + GCN1 chr12 120127202 120194715 - COX14 chr12 50112082 50120457 + GNAS chr20 58839718 58911192 + RPS6KA1 chr1 26529761 26575030 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.