exRNAdisease

Entry Detail

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General Information

Database ID: exR0428767 RNA Name: ACER3 RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 76860867 End Site(bp): 77026797 External Links: ENSG00000078124

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SLC39A13 chr11 47407132 47416496 + HLA-A chr6 29941260 29945884 + BANP chr16 87949244 88077318 + ARCN1 chr11 118572390 118603033 + PPIB chr15 64155812 64163205 - NDUFC2-KCTD14 chr11 78016971 78079865 - CCT2 chr12 69585426 69601570 + PTRH2 chr17 59674636 59707626 - TBC1D4 chr13 75283503 75482169 - NDUFC2 chr11 78068297 78079862 - KLHL7 chr7 23105758 23177914 + EIF3C chr16 28688558 28735730 + DNAJB6 chr7 157335381 157417439 + RPS10-NUDT3 chr6 34284887 34426071 - RPS10 chr6 34417454 34426069 - C22orf39 chr22 19351368 19448232 - MRFAP1L1 chr4 6707701 6709865 - SLC3A2 chr11 62856102 62888875 + TSKU chr11 76782251 76798153 + DPH1 chr17 2030110 2043430 + SYAP1 chrX 16719612 16765340 + HNRNPH1 chr5 179614178 179634784 - SHMT2 chr12 57229573 57234935 + RPL27A chr11 8682788 8714759 + FAM3C chr7 121348878 121396364 - PRDX3 chr10 119167720 119178812 - CNN2 chr19 1026586 1039068 + NOTCH2 chr1 119911553 120100779 - CDC42SE2 chr5 131245493 131398447 + AC010422.3 chr19 12643831 12648397 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-27a-3p chr19 13836447 13836467 - hsa-miR-129-5p chr7 128207876 128207896 + hsa-miR-27b-3p chr9 95085505 95085525 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.