exRNAdisease

Entry Detail

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General Information

Database ID: exR0428768 RNA Name: ACHE RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 100889994 End Site(bp): 100896974 External Links: ENSG00000087085

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CPNE2 chr16 57092583 57148369 + GNAI2 chr3 50226292 50259362 + GOLGA7 chr8 41490396 41510980 + GORASP1 chr3 39096659 39108363 - HLA-A chr6 29941260 29945884 + PCDHGA1 chr5 141330571 141512981 + PCDHGA10 chr5 141412987 141512979 + PCDHGA11 chr5 141421047 141512975 + PCDHGA12 chr5 141430507 141512975 + PCDHGA2 chr5 141338760 141512975 + PCDHGA3 chr5 141343829 141512979 + PCDHGA4 chr5 141355021 141512975 + PCDHGA5 chr5 141364232 141512979 + PCDHGA6 chr5 141373914 141512979 + PCDHGA7 chr5 141382739 141512975 + PCDHGA8 chr5 141390157 141512979 + PCDHGA9 chr5 141402932 141512979 + PCDHGB1 chr5 141350102 141512979 + PCDHGB2 chr5 141360042 141512979 + PCDHGB3 chr5 141370242 141512975 + PCDHGB4 chr5 141387698 141512979 + PCDHGB5 chr5 141397987 141512979 + PCDHGB6 chr5 141408021 141512979 + PCDHGB7 chr5 141417645 141512979 + PCDHGC3 chr5 141475947 141512977 + PCDHGC4 chr5 141484997 141512979 + PCDHGC5 chr5 141489121 141512979 + PLD3 chr19 40348456 40380439 + UBQLN1 chr9 83659968 83707958 - UQCRHL chr1 15807169 15809348 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.