exRNAdisease

Entry Detail

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General Information

Database ID: exR0428769 RNA Name: ACIN1 RNA Type: mRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 23058564 End Site(bp): 23095614 External Links: ENSG00000100813

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HNRNPA2B1 chr7 26173057 26201529 - CD74 chr5 150400041 150412929 - EEF1G chr11 62559596 62574086 - MANEAL chr1 37793802 37801137 + CGN chr1 151510510 151538692 + LRRC58 chr3 120324509 120349354 - RGPD5 chr2 109792758 109857705 + IVNS1ABP chr1 185296388 185317273 - TTLL3 chr3 9808086 9855138 + SDHAF3 chr7 97117698 97181763 + JAGN1 chr3 9890574 9894349 + RPL39 chrX 119786504 119791630 - CFAP20 chr16 58113592 58129381 - PCDHGA3 chr5 141343829 141512979 + PCDHGA1 chr5 141330571 141512981 + ALDH7A1 chr5 126531200 126595362 - EEF1A1 chr6 73515750 73523797 - PMF1 chr1 156212993 156240042 + WWC3 chrX 10015562 10144478 + RACK1 chr5 181236897 181248096 - SFXN1 chr5 175477062 175529742 + TPT1 chr13 45333471 45341370 - MRPS7 chr17 75261674 75266376 + RNASEK chr17 7012417 7014532 + TRAF7 chr16 2155698 2178129 + CERK chr22 46684410 46738252 - TSC2 chr16 2047967 2089491 + CNP chr17 41966763 41977740 + RPL11 chr1 23691742 23696835 + PCDHGA10 chr5 141412987 141512979 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC027682.2 chr16 67542123 67542963 - AC124068.2 chr15 89335053 89336161 + AL132780.1 chr14 22929607 22956374 + AL355075.4 chr14 20343048 20343685 - AP001496.2 chr18 5232876 5238526 - AP005263.1 chr18 9102736 9254346 + BISPR chr19 17405686 17419324 + NEAT1 chr11 65422774 65445540 + XIST chrX 73820649 73852723 - Z83843.1 chrX 74209976 74213660 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.