exRNAdisease

Entry Detail

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General Information

Database ID: exR0428777 RNA Name: ACO2 RNA Type: mRNA Chromosome: chr22 Starnd: + Coordinate: Start Site(bp): 41469117 End Site(bp): 41528989 External Links: ENSG00000100412

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RASA4 chr7 102573807 102616757 - NOC2L chr1 944203 959309 - RPS17 chr15 82536750 82540459 - LAMA1 chr18 6941742 7117797 - DPYSL2 chr8 26514031 26658178 + MTIF2 chr2 55236595 55269347 - EDIL3 chr5 83940554 84384880 - NAMPT chr7 106248298 106286326 - CDH1 chr16 68737292 68835541 + AP002990.1 chr11 62559603 62591531 - DDX19B chr16 70289663 70335283 + IFITM1 chr11 313506 315272 + COMT chr22 19941733 19969975 + R3HDM2 chr12 57253762 57431005 - HNRNPK chr9 83968083 83980616 - TMBIM6 chr12 49707725 49764934 + TUBB chr6 30720352 30725426 + U2AF1L5 chr21 6484623 6499261 - WDR74 chr11 62832342 62841809 - IQCB1 chr3 121769761 121835079 - KIF26A chr14 104138723 104180894 + CDCA2 chr8 25459199 25507911 + RRP36 chr6 43021623 43034156 + PTPRS chr19 5158495 5340803 - HDGFL3 chr15 83112738 83207823 - DAP chr5 10679230 10761272 - CD52 chr1 26317958 26320523 + PSMA2 chr7 42916861 42932185 - COPG1 chr3 129249606 129277773 + FRMPD4 chrX 11822423 12724523 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC079781.5 chr7 97851688 97972985 - AC147651.4 chr7 603185 608482 + AC245033.4 chr15 82533175 82540008 - SNHG19 chr16 2154797 2155358 - SNHG7 chr9 136721366 136728184 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.