exRNAdisease

Entry Detail

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General Information

Database ID: exR0428780 RNA Name: ACOT13 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 24667035 End Site(bp): 24705065 External Links: ENSG00000112304

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CCT3 chr1 156308968 156367873 - CDC26 chr9 113255835 113275572 - PARP1 chr1 226360691 226408093 - MTRNR2L8 chr11 10507894 10509186 - NDRG4 chr16 58462846 58513628 + TMEM97 chr17 28319200 28328685 + CBX5 chr12 54230942 54280133 - RAF1 chr3 12583601 12664226 - ZBTB25 chr14 64449106 64505213 - SLC16A3 chr17 82228397 82261129 + FUT4 chr11 94543840 94549898 + TRIM69 chr15 44728988 44767829 + RPS15 chr19 1438358 1440494 + HNRNPUL2-BSCL2 chr11 62690275 62727384 - RPRD1A chr18 35984387 36067576 - EEF1A1 chr6 73515750 73523797 - HNRNPUL2 chr11 62712630 62727457 - AL121594.1 chr14 35122549 35317474 + PRPF38A chr1 52404602 52420836 + FZD3 chr8 28494205 28574267 + SMPDL3A chr6 122789049 122809720 + CALM3 chr19 46601074 46610782 + EFNA1 chr1 155127876 155134899 + EI24 chr11 125569280 125584684 + RND2 chr17 43025231 43032041 + TAF15 chr17 35713791 35864615 + PRRC1 chr5 127517609 127555089 + KDM1A chr1 23019443 23083689 + MSC chr8 71841549 71844468 - MFSD5 chr12 53251251 53254405 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand MIR17HG chr13 91347820 91354579 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.