exRNAdisease

Entry Detail

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General Information

Database ID: exR0428781 RNA Name: ACOT2 RNA Type: mRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 73567620 End Site(bp): 73575658 External Links: ENSG00000119673

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACOT1 chr14 73537143 73543796 + ACOT4 chr14 73591706 73596496 + ACOT6 chr14 73610945 73619888 + ACSL4 chrX 109624244 109733403 - AL136295.5 chr14 24147548 24166452 + ANKRD16 chr10 5861616 5889906 - CRABP2 chr1 156699606 156705816 - ESYT2 chr7 158730995 158830253 - GOT2 chr16 58707131 58734342 - LIN28A chr1 26410817 26429728 + MRPL4 chr19 10251901 10260055 + MRPS10 chr6 42206807 42217861 - MUC4 chr3 195746765 195811973 - NBN chr8 89933336 90003228 - PARK7 chr1 7954291 7985505 + RNF130 chr5 179911651 180072113 - RNF31 chr14 24146683 24160660 + RPL18 chr19 48615328 48619184 - RPS9 chr19 54200809 54249003 + SDC3 chr1 30869466 30908758 - SDHAF4 chr6 70566917 70589569 + SEMA5B chr3 122909082 123028605 - SIGIRR chr11 405716 417455 - SIVA1 chr14 104753147 104768494 + TARDBP chr1 11012344 11026420 + TMEM259 chr19 1009648 1021179 - TSC22D4 chr7 100463359 100479232 - TTI1 chr20 37983007 38033461 - UBC chr12 124911604 124917368 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.