exRNAdisease

Entry Detail

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General Information

Database ID: exR0428783 RNA Name: ACOT7 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 6264269 End Site(bp): 6394391 External Links: ENSG00000097021

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HMGA1 chr6 34236873 34246231 + CHAMP1 chr13 114314482 114337626 + ANKZF1 chr2 219229783 219236679 + PRR7 chr5 177446445 177456286 + PGS1 chr17 78378649 78425114 + GYPC chr2 126656133 126696667 + UBP1 chr3 33388336 33441371 - TRIP10 chr19 6737925 6751530 + MTRNR2L11 chr1 237943724 237945275 - CCT7 chr2 73233420 73253021 + SEMA7A chr15 74409289 74433958 - TLE3 chr15 70047790 70098176 - GJA1 chr6 121435595 121449727 + NAP1L1 chr12 76036585 76084958 - UBE2D2 chr5 139526431 139628434 + PPP6R1 chr19 55229779 55259017 - CUL4A chr13 113208193 113267108 + EPB41L3 chr18 5392381 5630700 - FXR1 chr3 180868141 180982753 + CSNK2A1 chr20 472498 543835 - ELP2 chr18 36129444 36180557 + OGT chrX 71533104 71575892 + EEF2 chr19 3976056 3985463 - MLYCD chr16 83899115 83951445 + ZNF675 chr19 23525631 23687220 - SHC1 chr1 154962298 154974395 - SLC25A6 chrX 1386152 1392113 - ZNF333 chr19 14689801 14733746 + RBM15B chr3 51391285 51397908 + TRIM11 chr1 228393673 228406835 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC116407.1 chr17 32141226 32143135 - AL117378.1 chr6 131901963 131920565 + AC009119.2 chr16 83929796 83931223 - AL139393.2 chr6 160926269 160943110 + DANCR chr4 52712404 52720351 + FGD5-AS1 chr3 14920347 14948424 - MIR155HG chr21 25561909 25575168 + TUG1 chr22 30969245 30979395 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.