exRNAdisease

Entry Detail

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General Information

Database ID: exR0428784 RNA Name: ACOT8 RNA Type: mRNA Chromosome: chr20 Starnd: - Coordinate: Start Site(bp): 45841721 End Site(bp): 45857405 External Links: ENSG00000101473

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BAHD1 chr15 40439721 40468236 + RPS14 chr5 150442635 150449739 - C19orf53 chr19 13774456 13778773 + B2M chr15 44711487 44718877 + CHST15 chr10 124007668 124093598 - HAUS7 chrX 153447666 153495516 - CANX chr5 179678628 179731641 + SRPK2 chr7 105110704 105399308 - SZRD1 chr1 16352575 16398145 + CCL3 chr17 36088256 36090169 - HVCN1 chr12 110627841 110704950 - MAP7D1 chr1 36155579 36180849 + VMP1 chr17 59707192 59842255 + NCF4 chr22 36860988 36878017 + WBP1 chr2 74458400 74460891 + SBK1 chr16 28259246 28323849 + SLC16A1 chr1 112911847 112957013 - ARPC4 chr3 9792495 9807726 + CIC chr19 42268537 42295797 + PPP2R5C chr14 101761798 101927989 + CDK2 chr12 55966781 55972789 + GCSAM chr3 112120839 112133270 - EP400 chr12 131949942 132080460 + ABCD4 chr14 74285269 74303055 - RPL27A chr11 8682788 8714759 + PYURF chr4 88520998 88523776 - SAP18 chr13 21140514 21149084 + H6PD chr1 9234775 9271337 + NOP53 chr19 47745546 47757058 + TRIM45 chr1 117111060 117122587 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand BX890604.2 chrX 3817528 3937855 - MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.