exRNAdisease

Entry Detail

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General Information

Database ID: exR0428786 RNA Name: ACOX1 RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 75941507 End Site(bp): 75979177 External Links: ENSG00000161533

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPS19 chr19 41860255 41872925 + SAP18 chr13 21140514 21149084 + LAMA3 chr18 23689443 23956222 + ZNF512 chr2 27582969 27623217 + ELAC2 chr17 12991612 13018065 - C3orf52 chr3 112086335 112131004 + MAZ chr16 29806106 29811164 + POU5F1 chr6 31164337 31180731 - ZNF544 chr19 58228594 58277495 + NUP205 chr7 135557917 135648757 + OPA1 chr3 193593144 193697811 + KIF14 chr1 200551497 200620751 - WDR26 chr1 224385143 224437033 - ELF4 chrX 130064874 130110716 - ASXL1 chr20 32358330 32439319 + NRF1 chr7 129611720 129757082 + SMC3 chr10 110567691 110604636 + OSBPL10 chr3 31657890 32077580 - PSAP chr10 71816298 71851325 - TOX4 chr14 21476597 21499175 + PPP6R1 chr19 55229779 55259017 - RPL13A chr19 49487554 49492308 + TNFRSF13B chr17 16929816 16972118 - MREG chr2 215942584 216034096 - NDUFV1 chr11 67605653 67612554 + PPM1G chr2 27381195 27409591 - HLA-A chr6 29941260 29945884 + NOP14 chr4 2937933 2963406 - DCTPP1 chr16 30423615 30430030 - RPL10L chr14 46651010 46651781 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC138761.1 chr17 22266395 22288301 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.