exRNAdisease

Entry Detail

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General Information

Database ID: exR0428791 RNA Name: ACP5 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 11574660 End Site(bp): 11579008 External Links: ENSG00000102575

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTG1 chr17 81509971 81523847 - AL669918.1 chr6 32813767 32838822 - ATP5F1D chr19 1241746 1244825 + B2M chr15 44711487 44718877 + CCT3 chr1 156308968 156367873 - CD226 chr18 69831158 69961803 - COX4I1 chr16 85798633 85807068 + COX6C chr8 99873200 99893707 - ENO1 chr1 8861000 8879190 - GALNT6 chr12 51351247 51392867 - HLA-B chr6 31269491 31357188 - IRAK1 chrX 154010506 154019902 - LTA chr6 31572054 31574324 + NCAPD2 chr12 6493356 6531955 + NME3 chr16 1770286 1771730 - PFN1 chr17 4945652 4949061 - PPP4R3B chr2 55547292 55618880 - PRR7 chr5 177446445 177456286 + RBM33 chr7 155644451 155781485 + RNASET2 chr6 166929504 166957191 - RPL4 chr15 66498015 66524532 - SLC25A6 chrX 1386152 1392113 - SMAD2 chr18 47808957 47931146 - SNRNP40 chr1 31259568 31296788 - TAP2 chr6 32821833 32838770 - TERF2IP chr16 75647773 75761872 + UBC chr12 124911604 124917368 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand SNHG16 chr17 76557764 76565348 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.