exRNAdisease

Entry Detail

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General Information

Database ID: exR0428792 RNA Name: ACP6 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 147629652 End Site(bp): 147670524 External Links: ENSG00000162836

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD12 chr20 25294742 25390835 - ACSL1 chr4 184755595 184826818 - BICD2 chr9 92711363 92764833 - CHERP chr19 16517894 16542437 - CHRNB1 chr17 7445061 7457710 + COX4I1 chr16 85798633 85807068 + CPSF1 chr8 144393229 144409335 - DERL3 chr22 23834503 23839128 - DST chr6 56457987 56954649 - FBXO4 chr5 41925254 41941743 + GDE1 chr16 19501693 19522123 - GLCE chr15 69160584 69272217 + GLIS3 chr9 3824127 4348392 - IFITM1 chr11 313506 315272 + IFITM2 chr11 307631 315272 + NUP214 chr9 131125586 131234663 + PARP14 chr3 122680839 122730840 + PCNA chr20 5114953 5126626 - PHF21B chr22 44881162 45010005 - PKM chr15 72199029 72231822 - PPRC1 chr10 102132994 102150333 + RPL11 chr1 23691742 23696835 + RPL5 chr1 92832013 92841924 + SCD chr10 100347233 100364826 + TGFBRAP1 chr2 105264391 105329735 - TRAM2 chr6 52497408 52577060 - TUBG2 chr17 42659284 42667006 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC113189.4 chr17 7439506 7445966 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.